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Fatal Disseminated Hemorrhagic Toxoplasmic Encephalitis as the Initial Manifestation of AIDS
Ann Neurol 29:683-686, Wijdicks,E.F.M.,et al, 1991
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Article Abstract
A 28-year-old woman presented with progressive coma after being asymptomatic for 1 year after the demonstration of seropositivity for human immunodeficiency virus and high serum immunoglobulin G toxoplasma titers.Computed tomographic scanning showed multiple rounded cerebral hemorrhages and massive cerebral edema.Postmortem examination disclosed Toxoplasma Gondii cysts scattered throughout the brain.An overwhelming fatal toxoplasmosis associated with multiple cerebral hemorrhages may be the first presentation of the acquired immunodeficiency syndrome.We raise the possibility that frequent neuroradiological monitoring may be indicated in asymptomatic human immunodeficiency virus-infected patients with high immuloglobulin G toxoplasma titers.
 
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acquired immunodeficiency syndrome
CAT scan
CAT scan,abnormal
coma
human immunodeficiency virus type 1
intracerebral hemorrhage
intracerebral hemorrhage,multiple
mortality
toxoplasma gondii
toxoplasmosis,acquired
toxoplasmosis,CNS

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